Montaño López, F.J., B., González-Acosta, C.S., Cardona-Felix, M., Muñoz-Ochoa & J.A., Sanchez-Burgos (2023). Coastal Sediments of La Paz Bay BCS: Bacteria Reserve with Biotechnological Potential. Springer, Singapore (Ed.), Microbial Biodiversity, Biotechnology and Ecosystem Sustainability. pp.26. DOI: 10.1007/978-981-19-4336-2_11.
F. J. Montaño López, Bárbara González-Acosta 1, Cesar Salvador Cardona-Felix 1, Mauricio Muñoz-Ochoa 1 y Jorge A. Sanchez-Burgos
Coastal marine sediments are ecosystems rich in nutrientsand microorganisms, these environments are considered to be highly competitive,so these microorganisms have developed strategies that allow them to regulateor inhibit the growth of other microbial populations. In sediments obtainedfrom different locations in the La Paz Bay, in Baja California Sur México,different microorganisms have been identified that, according to theirmorphological, biochemical and molecular characteristics, belong to a group ofGram-positive bacteria known as actinobacteria. These bacteria have been shownto have the ability to grow in extreme conditions of low nutrient concentrations,and have the capacity of generating micro-ecosystems based on the production ofsecondary metabolites that allow them to develop properly in that ecosystem.Among the genera present in these ecosystems, the genus Streptomyces standsout. Cultures of this bacterium, extracellular extracts rich in peptides andother low molecular weight bioactive compounds have been obtained, which havebeen shown to have antimicrobial effect against different pathogenic strains.Thanks to the identification and characterization of the strains present in themicrobial communities through massive sequencing techniques, it has beenpossible to infer the mechanisms by which these strains can carry out thesynthesis of antimicrobial compounds. Knowing the genes involved in thesynthesis of these metabolites, it is possible to design the appropriatemechanisms to carry out production at the laboratory level and to evaluatetheir activity using in silico and in vitro tools. The objective of thisproposal is to describe the species of actinomycetes that have been identifiedin the bay, that present antimicrobial activity and that are potentially usefulfor their subsequent use at the semi-industrial level.
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