Zavala-Norzagaray, A.A., A.A., Aguirre, U.A., Angulo-Zamudio, C.P., Ley-Quiñonez, H., Flores-Villaseñor, N., León-Sicairos, J., Velázquez-Román, F.R., Elorriaga-Verplancken, K.A., Zavala-Félix, C.E., Hart & A., Canizalez-Román (2022). Isolation,characterization, and antimicrobial susceptibility of bacteria isolated fromsea lion (Zalophus californianus) pups in northwestern Mexico. Journal of Wildlife Diseases. 58(3): 500-511. DOI: 10.7589/JWD-D-21-00183.
Alan A. Zavala-Norzagaray 1, A. Alonso Aguirre 2, Uriel A. Angulo-Zamudio 3, Cesar Paul Ley-Quiñonez 1, Héctor Flores-Villaseñor 3, Nidia León-Sicairos 4, Jorge Velázquez-Román 3, Fernando R. Elorriaga-Verplancken 5, Kevin A. Zavala-Félix 6, Catherine E. Hart 7 y Adrian Canizalez-Román 3
Bacterial infectionshave been documented in marine mammals for decades, and some are consideredemerging pathogens with zoonotic potential. The aerobic oral (n=16) and rectal(n=17) bacterial microbiota and their antimicrobial resistance werecharacterized for 17 apparently healthy California sea lion pups (Zalophuscalifornianus) captured with a hoop net in Farallon Island, Sinaloa, Mexico, in2016. Bacteriologic cultures, Analytical Profile Index, and PCR were used toidentify bacterial species. The Escherichia coli phylogenetic groups wereidentified by PCR, Salmonella serotypes were identified, and resistance toantibiotics was evaluated. Overall, 39 bacterial species were isolated,including E. coli and Salmonella spp. (35.9% each) and Pseudomonas aeruginosa(28.2%). For E. coli, UNKNOWN phylogroup was the most prevalent (57.7%),followed by the A phylogroup (37.1%). Most Salmonella serotypes were identifiedas Newport (92.8%); serotype Saintpaul was also identified (7.2%). Sea lionswith bacterial co-colonization included 24.2%, from which two bacterial specieswere isolated, and 3% with three species. Overall, 59% of bacteria wereresistant to at least one antibiotic tested, and 25.6% were extensively drugresistant. Bacteria were highly resistant to ampicillin and cefotaxime. Thisstudy demonstrates the importance of characterizing the microbiome of sealions, and the potential effect of pathogens with antimicrobial resistance onwildlife conservation and public health.
Palabras clave: Escherichia coli; Mexico; Salmonella Newport; Salmonella Saintpaul; sea lions; Zalophus californianus
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