Resumen del producto

Background and Objective:  Invertebrates comprises more than fifty percent of marine animals. Among them, sponges are the most prolific source of bioactive  compounds.  Suberites  aurantiacus  (S.  aurantiacus)  is an abundant sponge in Mexican Pacific, which has been  scarcely  studied,  for  this  reason  authors   screened   it   for   its   bioactivities. The current study proposed to determine the enzymatic inhibition and scavenger, toxic and antibacterial activities from S. aurantiacus.  Materials and Methods: S. aurantiacus samples were collected  in Magdalena   Bay,   Mexico.   The   ethanolic extract and its  fractions were assayed for their antioxidant effect using DPPH, ABTS and NO assays,  evaluated  their toxicity against Artemia salina (A. salina) and their antibacterial activity against Staphylococcus aureus (S. aureus), Bacillus subtilis (B. subtilis), Enterococcus  faecalis (E.  faecalis), Enterobacter  aerogenes (E.  aerogenes), Escherichia  coli (E.   coli)   and  Klebsiella   pneumoniae  (K.   pneumoniae)   as   well   as   their   inhibitory  effect  on "-glucosidase and -amylase”. Results: The results showed median lethal doses (LD₅₀) against A. salina < 1 mg mL G1  for two fractions and a  moderate antibacterial activity against Gram positive bacteria. Conclusion: In view of these results, S.  aurantiacus   could  be considered a potential source of antibacterial compounds.

Palabras clave: sponge; bactericide; toxicity; antioxidant; enzyme inhibition

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